Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23080510 | 1.00 | CYP3A4 (0.39) | CYP3A4 | |
| SCHEMBL6675166 | 0.82 | CYP3A4 (0.35) | CYP3A4 | |
| SCHEMBL28565540 | 0.76 | CYP3A4 (0.39) | CYP3A4 | |
| SCHEMBL16996620 | 0.68 | — | — | |
| SCHEMBL8806152 | 0.67 | CYP3A4 (0.32) | CYP3A4 | |
| SCHEMBL8183244 | 0.64 | ESR2 (0.32) | — | |
| SCHEMBL28913606 | 0.64 | — | — | |
| SCHEMBL23630740 | 0.64 | ESR2 (0.32) | — | |
| SCHEMBL13421816 | 0.64 | ESR2 (0.32) | — | |
| SCHEMBL12522502 | 0.64 | POLB (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928080-B | Fused ring gamma-amino acid derivative, preparation method and application thereof in medicine | 四川海思科制药有限公司 | 2020-12-25 | — | — | CN | disclosed |
| CN-106928080-A | Fused rings γ amino acid derivativges and preparation method thereof and in application pharmaceutically | 四川海思科制药有限公司 | 2017-07-07 | — | — | CN | disclosed |