Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13421816 | 1.00 | ESR2 (0.32) | ESR2ESR1 | |
| SCHEMBL8183244 | 1.00 | ESR2 (0.32) | ESR2ESR1 | |
| SCHEMBL6675166 | 0.67 | CYP3A4 (0.35) | — | |
| SCHEMBL24718077 | 0.64 | — | — | |
| SCHEMBL23080510 | 0.64 | CYP3A4 (0.39) | — | |
| SCHEMBL28160935 | 0.64 | CYP3A4 (0.39) | — | |
| SCHEMBL3224313 | 0.63 | CA1 (0.32) | ESR2 | |
| SCHEMBL15957272 | 0.63 | CA1 (0.32) | ESR2 | |
| SCHEMBL16996620 | 0.60 | — | — | |
| Ethylene SCHEMBL3215921 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11267786-B2 | [3.3.1] bicyclo compounds as indoleamine 2,3-dioxygenase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2022-03-08 | — | — | US | disclosed |
| US-20210214308-A1 | NOVEL [3.3.1] BICYCLO COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2021-07-15 | — | — | US | disclosed |
| US-20210214308-A1 | NOVEL [3.3.1] BICYCLO COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214308-A1 | NOVEL [3.3.1] BICYCLO COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS | IDO1, IDO2, KYNU | ESR2 4044/4885ESR1 4859/4885 |
| US-11267786-B2 | [3.3.1] bicyclo compounds as indoleamine 2,3-dioxygenase inhibitors | IDO1, IDO2, KYNU | ESR2 3930/4885ESR1 4859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.