SCHEMBL8183244

SCHEMBL8183244

O=C1CCC2C[C@H]1CCC21OCCO1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.32
ESR1 P03372 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23630740 1.00 ESR2 (0.32) ESR2ESR1
SCHEMBL13421816 1.00 ESR2 (0.32) ESR2ESR1
SCHEMBL6675166 0.67 CYP3A4 (0.35)
SCHEMBL24718077 0.64
SCHEMBL23080510 0.64 CYP3A4 (0.39)
SCHEMBL28160935 0.64 CYP3A4 (0.39)
SCHEMBL3224313 0.63 CA1 (0.32) ESR2
SCHEMBL15957272 0.63 CA1 (0.32) ESR2
SCHEMBL16996620 0.60
Ethylene SCHEMBL3215921 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008077556-A1 CYCLOALKYLAMINE SUBSTITUTED ISOQUINOLINE AND ISOQUINOLINONE DERIVATIVES SANOFI-AVENTIS (FR) 2008-07-03 WO disclosed