Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Hydroquinone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.60 |
| ▸ | HTR3A | P46098 | 2/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | BACE1 | P56817 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ABAT | P80404 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CA3 | P07451 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroquinone SCHEMBL27820185 | 0.96 | ALDH1A1 (0.63) | ALDH1A1KDM4ETAAR1HTR3AHTR1A | |
| Hydroquinone SCHEMBL15514721 | 0.93 | ALDH1A1 (0.60) | ALDH1A1KDM4ETAAR1HTR3AHTR1A | |
| Hydroquinone SCHEMBL28165945 | 0.93 | ALDH1A1 (0.60) | ALDH1A1KDM4ETAAR1HTR3AHTR1A | |
| 4-Aminophenol SCHEMBL28330028 | 0.84 | ALDH1A1 (0.77) | ALDH1A1KDM4ETAAR1HTR3AHTR1A | |
| Phenol SCHEMBL28165624 | 0.84 | TDP1 (0.65) | ALDH1A1KDM4ETAAR1HTR3AHTR1A | |
| Phenol SCHEMBL28151254 | 0.84 | TDP1 (0.65) | ALDH1A1KDM4ETAAR1HTR3AHTR1A | |
| Hydroquinone SCHEMBL11759332 | 0.83 | ALDH1A1 (0.57) | ALDH1A1KDM4ETAAR1HTR3AHTR1A | |
| Hydroquinone SCHEMBL3978237 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KDM4ETAAR1HTR3AHTR1A | |
| Hydroquinone SCHEMBL9312654 | 0.80 | — | — | |
| Phenol SCHEMBL11658010 | 0.80 | TDP1 (0.69) | ALDH1A1KDM4ETAAR1HTR3AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107020107-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-08-08 | — | — | CN | claimed |
| CN-107008392-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-08-04 | — | — | CN | claimed |
| CN-107051492-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-08-18 | — | — | CN | disclosed |
| CN-107008280-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-08-04 | — | — | CN | disclosed |
| CN-107008349-A | The preparation method of ozone Heterogeneous oxidation solid catalyst | 四川师范大学 | 2017-08-04 | — | — | CN | disclosed |