Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTR1B | P28222 | 7/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3120591 | 0.85 | KDM4E (0.53) | ALDH1A1HSD17B10KDM4EHPGDHTR1B | |
| SCHEMBL16178487 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HSD17B10KDM4EHPGDHTR1B | |
| SCHEMBL17537056 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HSD17B10KDM4EHPGDHTR1B | |
| SCHEMBL8026143 | 0.83 | ALDH1A1 (0.55) | ALDH1A1HSD17B10KDM4EHPGDHTR1B | |
| SCHEMBL17271346 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HSD17B10KDM4EHPGDHTR1B | |
| SCHEMBL10713653 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KDM4EHPGDHTR1B | |
| SCHEMBL15157392 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HSD17B10KDM4EHPGDHTR1B | |
| SCHEMBL20002024 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HSD17B10KDM4EHPGDHTR1B | |
| SCHEMBL11064711 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HSD17B10KDM4EHPGDHTR1B | |
| SCHEMBL31091502 | 0.77 | ALDH1A1 (0.62) | ALDH1A1HSD17B10KDM4EHPGDHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104603118-B | Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators of the orphan nuclear receptor ROR γ | 菲尼克斯药品股份公司 | 2017-10-03 | — | — | CN | disclosed |
| CN-107007597-A | It is used as the thiazole of orphan nuclear receptor ROR γ instrumentalities through formamide or sulfonamide substitutions and the pharmaceutical applications of related derivatives | 菲尼克斯药品股份公司 | 2017-08-04 | — | — | CN | disclosed |