Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30474592 | 0.81 | PRMT5 (0.41) | SLC9A1KEAP1HSD11B1SMN1; SMN2RECQL | |
| SCHEMBL16506376 | 0.79 | PDE10A (0.38) | PDPK1SLC9A1KEAP1HSD11B1PDE10A | |
| SCHEMBL31439989 | 0.78 | BACE1 (0.38) | PDPK1SLC9A1KEAP1PDE10APRMT5 | |
| SCHEMBL21631683 | 0.78 | PTPN11 (0.33) | — | |
| SCHEMBL27229417 | 0.78 | PDPK1 (0.37) | PDPK1SLC9A1KEAP1PDE10ABACE1 | |
| SCHEMBL23229326 | 0.76 | PTPN11 (0.32) | — | |
| SCHEMBL28860343 | 0.75 | PDPK1 (0.35) | PDPK1SLC9A1KEAP1PDE10A | |
| SCHEMBL21631391 | 0.75 | HTR1A (0.34) | SMN1; SMN2 | |
| SCHEMBL31211051 | 0.74 | PDPK1 (0.34) | PDPK1SLC9A1KEAP1PDE10A | |
| SCHEMBL27359788 | 0.74 | PDE10A (0.38) | PDPK1SLC9A1KEAP1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001330-A | Histone demethylase inhibitors | 赛尔基因昆蒂赛尔研究公司 | 2017-08-01 | — | — | CN | disclosed |