Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | XIAP | P98170 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31439989 | 0.79 | BACE1 (0.38) | PDE10APDPK1SLC9A1KEAP1BACE1 | |
| SCHEMBL13106159 | 0.77 | PARP1 (0.41) | CHRM4SLC9A1KEAP1NR1H2NR1H3 | |
| SCHEMBL28860343 | 0.77 | PDPK1 (0.35) | PDE10APDPK1SLC9A1KEAP1 | |
| SCHEMBL31211051 | 0.75 | PDPK1 (0.34) | PDE10APDPK1SLC9A1KEAP1NPC1 | |
| SCHEMBL21631687 | 0.74 | CHRM4 (0.38) | LMNATP53THRBTLR9L3MBTL1 | |
| SCHEMBL16369714 | 0.74 | CHRM4 (0.40) | LMNATP53THRBTLR9L3MBTL1 | |
| SCHEMBL13106169 | 0.73 | HSD11B1 (0.41) | PDE10ALMNAL3MBTL1CHRM4ALDH1A1 | |
| SCHEMBL20604737 | 0.71 | CYP1A2 (0.40) | LMNATP53TSHRALDH1A1 | |
| SCHEMBL359647 | 0.71 | LMNA (0.41) | LMNATP53THRBTLR9L3MBTL1 | |
| SCHEMBL16506029 | 0.69 | MAPK13 (0.40) | LMNATP53THRBTLR9L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260138978-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M1 | VANDERBILT UNIV (US) | 2026-05-21 | — | — | US | disclosed |
| US-20240228489-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M1 | VANDERBILT UNIVERSITY | 2024-07-11 | — | — | US | disclosed |
| CN-105801550-B | Novel chromene kinase modulator | 理森制药股份公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-104910148-B | Aminotriazole(ATA) and pyridine and its as kinase inhibitor purposes | 西格诺药品有限公司 | 2017-06-27 | — | — | CN | disclosed |
| EP-3036235-B1 | NEW BIS-AMIDO PYRIDINES | BOEHRINGER INGELHEIM INT (DE) | 2017-04-19 | — | — | EP | disclosed |
| CN-105801550-A | Novel benzopyran kinase modulators | 理森制药股份公司 | 2016-07-27 | — | — | CN | disclosed |
| EP-3036235-A1 | NEW BIS-AMIDO PYRIDINES | Boehringer Ingelheim International GmbH (DE) | 2016-06-29 | — | — | EP | disclosed |
| CN-103052633-B | The indazole derivatives that amide group replaces is birdsed of the same feather flock together (ADP-ribose) AG14361 | BETTA PHARMACEUTICALS Co.,Ltd. (CN) | 2016-03-23 | — | — | CN | disclosed |
| US-9249151-B2 | Bis-amido pyridines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-02-02 | — | — | US | disclosed |
| US-20150057286-A1 | NEW BIS-AMIDO PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-02-26 | — | — | US | disclosed |
| WO-2015025018-A1 | NEW BIS-AMIDO PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-02-26 | — | — | WO | disclosed |
| CN-103450085-A | Preparation method of pazopanib hydrochloride key intermediate | ASYMCHEM LAB TIANJIN CO LTD | 2013-12-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150057286-A1 | NEW BIS-AMIDO PYRIDINES | SMARCC1, MKI67, SMARCC2 | PDE10A 1699/4885PDPK1 1497/4885LMNA 98/4885 |
| US-20240228489-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M1 | CHRM1, CHRM3, CHRM2 | PDE10A 925/4885PDPK1 649/4885LMNA 4107/4885 |
| US-20260138978-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M1 | CHRM1, CHRM4, CHRM2 | PDE10A 1865/4885PDPK1 1102/4885LMNA 4150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.