Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 2/20 | 0.33 |
| ▸ | DNTT | P04053 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2816221 | 1.00 | POLA1 (0.33) | POLA1DNTTPOLBCA12CA9 | |
| SCHEMBL30897118 | 0.84 | CA12 (0.33) | CA12CA9 | |
| SCHEMBL2813755 | 0.72 | TSHR (0.35) | CA12CA9ALDH1A1 | |
| SCHEMBL2813758 | 0.72 | TSHR (0.35) | CA12CA9ALDH1A1 | |
| SCHEMBL10871135 | 0.67 | POLA1 (0.38) | POLA1DNTTPOLB | |
| SCHEMBL13168805 | 0.65 | HSD17B3 (0.35) | ALDH1A1 | |
| SCHEMBL2816300 | 0.64 | CA12 (0.31) | CA12CA9 | |
| SCHEMBL11548379 | 0.60 | CA12 (0.42) | POLBCA12CA9 | |
| SCHEMBL8354298 | 0.60 | CA12 (0.42) | POLBCA12CA9ALDH1A1 | |
| SCHEMBL2290500 | 0.60 | CA12 (0.42) | POLBCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318804-B2 | Antiviral activity of cyclopentene nitro-ester and derivatives | UNIVERSITY OF SOUTH FLORIDA (US) | 2012-11-27 | — | — | US | disclosed |
| US-8236853-B1 | Formation of cyclopentene nitro-ester and derivatives | UNIVERSITY OF SOUTH FLORIDA (US) | 2012-08-07 | — | — | US | disclosed |
| US-20100249230-A1 | ANTIVIRAL ACTIVITY OF CYCLOPENTENE NITRO-ESTER AND DERIVATIVES | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-09-30 | — | — | US | disclosed |
| WO-2009076397-A2 | ANTIVIRAL ACTIVITY OF CYCLOPENTENE NITRO-ESTER AND DERIVATIVES | UNIVERSITY OF SOUTH FLORIDA (US) | 2009-06-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249230-A1 | ANTIVIRAL ACTIVITY OF CYCLOPENTENE NITRO-ESTER AND DERIVATIVES | CYP51A1, CES2, DDT | POLA1 90/4885DNTT 365/4885POLB 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.