SCHEMBL28162736

SCHEMBL28162736

CN(C)C(=O)CC1COC1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.33
GAA P10253 1/20 0.33
ALDH1A1 P00352 1/20 0.33
DPP4 P27487 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26089172 0.79
SCHEMBL20683255 0.78 PIK3CD (0.37) LTA4HGAAALDH1A1DPP4
SCHEMBL16399328 0.78
SCHEMBL12903289 0.74
SCHEMBL16055768 0.74 KMT2A (0.42) LTA4HGAAALDH1A1DPP4
SCHEMBL2375038 0.74 LTA4H (0.33) LTA4HDPP4
SCHEMBL15777293 0.73
SCHEMBL6042973 0.73 KMT2A (0.45) ALDH1A1DPP4
SCHEMBL8684586 0.73 KMT2A (0.45) ALDH1A1DPP4
SCHEMBL18505910 0.73 SLC6A1 (0.38) GAAALDH1A1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104837818-B It can be used as the acid amides of pyridine 2 of CB2 activators 霍夫曼-拉罗奇有限公司 2017-07-14 CN claimed