Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | WEE1 | P30291 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28278675 | 0.91 | ATM (0.66) | ATMMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL3886263 | 0.87 | BCHE (0.52) | TTRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL3231588 | 0.84 | ATM (0.50) | ATMTTRMAPTKDM4EALDH1A1 | |
| SCHEMBL11378517 | 0.80 | HTT (0.57) | ATMMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL30777875 | 0.79 | CYP2C9 (0.50) | TTRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL26768260 | 0.79 | CYP2C9 (0.50) | TTRMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL31087387 | 0.78 | MGAM (0.51) | MAPTKDM4EALDH1A1HPGDHTT | |
| SCHEMBL13633649 | 0.78 | L3MBTL1 (0.61) | ATMMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL1538292 | 0.78 | GPR3 (0.64) | ATMMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL9869325 | 0.77 | KDM4E (0.61) | TTRMAPTKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107056702-A | A kind of ether derivative of acridone two and its production and use | 复旦大学 | 2017-08-18 | — | — | CN | disclosed |