Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | PARP1 | P09874 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CD38 | P28907 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28165039 | 0.87 | FABP4 (0.62) | FABP4KDM4EKMT2AALDH1A1MAPT | |
| SCHEMBL28164552 | 0.82 | FABP4 (0.43) | FABP4KDM4EPARP1KMT2AATM | |
| SCHEMBL28164438 | 0.82 | FABP4 (0.43) | FABP4KDM4EPARP1KMT2AATM | |
| Hydrochloric Acid SCHEMBL28263901 | 0.82 | FABP4 (0.43) | FABP4KDM4EPARP1KMT2AATM | |
| SCHEMBL19924466 | 0.82 | FABP4 (0.43) | FABP4KDM4EPARP1KMT2AATM | |
| SCHEMBL29782416 | 0.74 | FABP4 (0.38) | FABP4KDM4EPARP1ATMALDH1A1 | |
| SCHEMBL29782685 | 0.72 | FABP4 (0.36) | FABP4KDM4EPARP1KMT2AALDH1A1 | |
| SCHEMBL39964 | 0.71 | KDM4E (0.52) | KDM4EPARP1ALDH1A1GAAMAPT | |
| Hydrochloric Acid SCHEMBL4562961 | 0.69 | PARP1 (0.50) | KDM4EPARP1ALDH1A1GAAMAPT | |
| SCHEMBL28837954 | 0.69 | FABP4 (0.41) | FABP4PARP1KMT2AATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511209-A | It can be used as the indole carboxamides compound of kinase inhibitor | BRISTOL MYERS SQUIBB CO | 2019-11-29 | — | — | CN | claimed |
| CN-107108583-A | Indole carboxamide compounds useful as kinase inhibitors | 百时美施贵宝公司 | 2017-08-29 | — | — | CN | claimed |
| CN-110511209-A | It can be used as the indole carboxamides compound of kinase inhibitor | BRISTOL MYERS SQUIBB CO | 2019-11-29 | — | — | CN | disclosed |
| CN-107108583-A | Indole carboxamide compounds useful as kinase inhibitors | 百时美施贵宝公司 | 2017-08-29 | — | — | CN | disclosed |