Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MYC | P01106 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28164948 | 0.69 | FABP4 (0.48) | FABP4MEN1KMT2AMYCLMNA | |
| Hydrochloric Acid SCHEMBL28531727 | 0.68 | MAPT (0.49) | MEN1KMT2ALMNATDP1ALDH1A1 | |
| SCHEMBL28499183 | 0.68 | LMNA (0.43) | MEN1KMT2ALMNATDP1ALDH1A1 | |
| SCHEMBL28837916 | 0.68 | MAOA (0.38) | FABP4MEN1KMT2ALMNATDP1 | |
| Hydrochloric Acid SCHEMBL28263901 | 0.68 | FABP4 (0.43) | FABP4MEN1KMT2AMYCLMNA | |
| SCHEMBL28164552 | 0.68 | FABP4 (0.43) | FABP4MEN1KMT2AMYCLMNA | |
| SCHEMBL28164438 | 0.68 | FABP4 (0.43) | FABP4MEN1KMT2AMYCLMNA | |
| SCHEMBL28165039 | 0.66 | FABP4 (0.62) | FABP4MEN1KMT2AMYCLMNA | |
| SCHEMBL3113613 | 0.65 | MAPT (0.32) | FABP4MEN1KMT2AALDH1A1MAPT | |
| Formamide SCHEMBL4205324 | 0.65 | MAPT (0.46) | MEN1KMT2ALMNATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028617-A | Heterocyclic inhibitors of CBP/EP300 and their use in the treatment of cancer | 基因泰克公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-109476641-B | Heterocyclic inhibitors of CBP/EP300 and their use in the treatment of cancer | 基因泰克公司 | 2022-07-05 | — | — | CN | disclosed |