Pyridaben

Pyridaben

SCHEMBL28165366

CC(C)(C)c1ccc(CSc2cnn(C(C)(C)C)c(=O)c2Cl)cc1.c1ccsc1

nearest known ligand 0.85

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.85
KMT2A Q03164 2/20 0.85
NPC1 O15118 1/20 0.85
GALR3 O60755 1/20 0.85
NR2F2 P24468 1/20 0.85
GPR183 P32249 1/20 0.85
RAB9A P51151 1/20 0.85
GPR35 Q9HC97 1/20 0.85
MAPT P10636 4/20 0.49
GAA P10253 2/20 0.49
PKM P14618 2/20 0.49
SCN9A Q15858 3/20 0.40
SCN5A Q14524 2/20 0.39
LMNA P02545 5/20 0.38
SMN1; SMN2 Q16637 5/20 0.38
HPGD P15428 3/20 0.38
HTT P42858 3/20 0.38
ALDH1A1 P00352 3/20 0.38
PPARG P37231 3/20 0.38
NCOA2 Q15596 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridaben SCHEMBL8372466 0.92 MEN1 (1.00) MEN1KMT2ANPC1GALR3NR2F2
Pyridaben SCHEMBL27429 0.92 MEN1 (1.00) MEN1KMT2ANPC1GALR3NR2F2
Pyridaben SCHEMBL28313875 0.87 MEN1 (0.80) MEN1KMT2ANPC1GALR3NR2F2
Pyridaben SCHEMBL27522162 0.84 MEN1 (0.78) MEN1KMT2ANPC1GALR3NR2F2
SCHEMBL9240100 0.83 NPC1 (0.82) MEN1KMT2ANPC1GALR3NR2F2
SCHEMBL9775193 0.83 NPC1 (0.81) MEN1KMT2ANPC1GALR3NR2F2
SCHEMBL9234574 0.83 RAB9A (0.77) MEN1KMT2ANPC1GALR3NR2F2
SCHEMBL9235604 0.81 RAB9A (0.75) MEN1KMT2ANPC1GALR3NR2F2
SCHEMBL9380142 0.81 KMT2A (0.79) MEN1KMT2ANPC1GALR3NR2F2
SCHEMBL10771363 0.81 NPC1 (0.78) MEN1KMT2ANPC1GALR3NR2F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106995420-A One class thiadiazoles oxime ether methoxy base acrylate derivative and its production and use 南开大学 2017-08-01 CN claimed