Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.47 |
| ▸ | CCR5 | P51681 | 2/20 | 0.47 |
| ▸ | CCR8 | P51685 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CBFB | Q13951 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28444694 | 0.86 | NPC1 (0.44) | CCR1CCR5CCR8NPC1ALDH1A1 | |
| SCHEMBL28443642 | 0.86 | ALDH1A1 (0.44) | CCR1CCR5CCR8NPC1ALDH1A1 | |
| SCHEMBL15986584 | 0.86 | NPC1 (0.44) | CCR1CCR5CCR8NPC1ALDH1A1 | |
| SCHEMBL15902913 | 0.86 | ALDH1A1 (0.44) | CCR1CCR5CCR8NPC1ALDH1A1 | |
| SCHEMBL28165762 | 0.85 | KDM4E (0.47) | CCR1CCR5CCR8NPC1ALDH1A1 | |
| SCHEMBL9585147 | 0.82 | GRM4 (0.42) | CCR1CCR5CCR8NPC1ALDH1A1 | |
| SCHEMBL10696996 | 0.82 | KMT2A (0.46) | NPC1ALDH1A1CYP2D6CYP2C19KDM4E | |
| SCHEMBL15907336 | 0.79 | PIN1 (0.42) | CCR1CCR5CCR8NPC1ALDH1A1 | |
| SCHEMBL15903036 | 0.79 | PIN1 (0.51) | NPC1ALDH1A1KDM4EPIN1TDP1 | |
| SCHEMBL28432128 | 0.79 | CHRM5 (0.45) | NPC1ALDH1A1CYP2D6CYP2C19FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107011250-B | Synthetic method and application of 2- (2, 6-dichlorophenoxy) pyridine compound | 温州医科大学 | 2020-08-11 | — | — | CN | disclosed |
| CN-107011250-A | One kind 2（2,6 dichlorophenoxies）The preparation method and use of pyridine compounds | 温州医科大学 | 2017-08-04 | — | — | CN | disclosed |