Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16616389 | 0.93 | SMN1; SMN2 (0.42) | HSD17B10SMN1; SMN2MAPK1KDM4EMAPT | |
| SCHEMBL28166124 | 0.88 | GABRP (0.43) | SMN1; SMN2KDM4EMAPTPLA2G2AGABRP | |
| SCHEMBL4164161 | 0.88 | HSP90AA1 (0.41) | HSD17B10SMN1; SMN2MAPK1KDM4EMAPT | |
| SCHEMBL16616317 | 0.88 | KEAP1 (0.47) | SMN1; SMN2MAPK1KDM4EHSP90AA1GABRP | |
| SCHEMBL4164158 | 0.81 | HSP90AA1 (0.45) | HSD17B10SMN1; SMN2MAPK1KDM4EMAPT | |
| SCHEMBL16616923 | 0.80 | NPC1 (0.46) | SMN1; SMN2KDM4EMAPTPLA2G2AGABRP | |
| SCHEMBL11377753 | 0.77 | CYP46A1 (0.49) | HSD17B10SMN1; SMN2MAPK1GABRA1GABRG2 | |
| SCHEMBL16624279 | 0.76 | NPC1 (0.47) | SMN1; SMN2KDM4EMAPTPLA2G2ANFKB1 | |
| SCHEMBL16616378 | 0.76 | HSP90AA1 (0.41) | HSD17B10SMN1; SMN2MAPK1KDM4EMAPT | |
| SCHEMBL4184727 | 0.75 | GABRP (0.47) | HSD17B10KDM4EGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612158-B | The somatostatin receptor hypotype 5 (SSTR5) antagonist | 武田药品工业株式会社 | 2017-06-30 | — | — | CN | disclosed |