SCHEMBL28166222

SCHEMBL28166222

CS(=O)(=O)Oc1c(-c2ccccc2-c2ccccc2)cc(F)c(F)c1F

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 11/20 0.41
PTGS1 P23219 2/20 0.36
ACLY P53396 3/20 0.36
SCN9A Q15858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30278243 0.72 BACE1 (0.38) PTGS2PTGS1NPSR1
SCHEMBL25273770 0.72 BACE1 (0.38) PTGS2PTGS1NPSR1
SCHEMBL27635813 0.72 PTGS2 (0.52) PTGS2PTGS1NPSR1
SCHEMBL29098923 0.72 PDE4B (0.47) PTGS2PTGS1ACLY
SCHEMBL29546745 0.72 PDE4B (0.47) PTGS2PTGS1ACLY
SCHEMBL28789939 0.71 BACE1 (0.37) PTGS2PTGS1
SCHEMBL27456101 0.70 KMT2A (0.41) PTGS2
SCHEMBL27635812 0.70 PTGS2 (0.58) PTGS2PTGS1
SCHEMBL6517496 0.69 ACLY (0.44) PTGS2ACLYNPSR1
SCHEMBL3742731 0.69 CA1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104640902-B It is conjugated based polymer, the electron donating property organic material for having used the conjugation based polymer, photovoltaic element material and photovoltaic element 东丽株式会社 2017-09-01 CN disclosed