Tetrahydrofuran

Tetrahydrofuran

SCHEMBL28166234

C1CCOC1.CCCCCN

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 9/20 0.57
TSHR P16473 3/20 0.57
ALDH1A1 P00352 2/20 0.57
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
EPHX1 P07099 1/20 0.57
KEAP1 Q14145 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
LMNA P02545 1/20 0.35
NFKB1 P19838 1/20 0.35
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL1193018 0.98 DNM1 (0.62) DNM1TSHRALDH1A1MEN1KMT2A
Hexadecylamine SCHEMBL11227679 0.98 DNM1 (0.62) DNM1TSHRALDH1A1MEN1KMT2A
Tetrahydrofuran SCHEMBL28210848 0.98 DNM1 (0.62) DNM1TSHRALDH1A1MEN1KMT2A
Tetrahydrofuran SCHEMBL1728990 0.92 DNM1 (0.46) DNM1TSHRALDH1A1MEN1KMT2A
Tetrahydrofuran SCHEMBL9015780 0.92 DNM1 (0.46) DNM1TSHRALDH1A1MEN1KMT2A
Tetrahydrofuran SCHEMBL28585403 0.92 DNM1 (0.46) DNM1TSHRALDH1A1MEN1KMT2A
Tetrahydrofuran SCHEMBL8250456 0.90 DNM1 (0.43) DNM1TSHRALDH1A1MEN1KMT2A
Dioxane SCHEMBL27580074 0.90 DNM1 (0.63) DNM1TSHRALDH1A1MEN1KMT2A
SCHEMBL28303104 0.90 DNM1 (0.63) DNM1TSHRALDH1A1MEN1KMT2A
Dioxane SCHEMBL27305245 0.87 DNM1 (0.68) DNM1TSHRALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109868298-A Preparation method of tetrahydrofuran-2-formic acid 上海弈柯莱生物医药科技有限公司 2019-06-11 CN disclosed
CN-104903329-B method for producing aromatic compound 日本化药株式会社 2017-07-04 CN disclosed