Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL28585403 | 1.00 | DNM1 (0.46) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Tetrahydrofuran SCHEMBL1728990 | 1.00 | DNM1 (0.46) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Tetrahydrofuran SCHEMBL8250456 | 0.97 | DNM1 (0.43) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Tetrahydrofuran SCHEMBL28166234 | 0.92 | DNM1 (0.57) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Tetrahydrofuran SCHEMBL23321480 | 0.91 | DNM1 (0.39) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Tetrahydrofuran SCHEMBL8197168 | 0.91 | DNM1 (0.39) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Hexadecylamine SCHEMBL11227679 | 0.90 | DNM1 (0.62) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Tetrahydrofuran SCHEMBL1193018 | 0.90 | DNM1 (0.62) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Tetrahydrofuran SCHEMBL28210848 | 0.90 | DNM1 (0.62) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Dioxane SCHEMBL8746856 | 0.89 | DNM1 (0.50) | DNM1ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519126-A | COMBATTING DISEASES BY BIOCHEMICL INTERVENTION AT THE RNA AND DNA LEVEL | UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1996-05-21 | — | — | US | disclosed |
| EP-0406309-A4 | OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES | — | 1992-08-19 | — | — | EP | disclosed |
| EP-0406309-A1 | OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES | THE UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1991-01-09 | — | — | EP | disclosed |
| WO-1989009221-A1 | OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES | UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1989-10-05 | — | — | WO | disclosed |