SCHEMBL28166273

SCHEMBL28166273

CC(C)CCCC#CC1=CCCC1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.34
GRM5 P41594 2/20 0.34
FFAR1 O14842 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4212451 0.72
SCHEMBL6566285 0.64 TSHR (0.31)
SCHEMBL552152 0.64 CYP1A2 (0.34) CYP1A2GRM5FFAR1
SCHEMBL551632 0.63 FFAR1 (0.44) CYP1A2GRM5FFAR1
SCHEMBL11744662 0.61
SCHEMBL11745324 0.61
SCHEMBL18530722 0.61 CYP1A2 (0.49) CYP1A2GRM5FFAR1
SCHEMBL31041689 0.61 SMN1; SMN2 (0.53) SMN1; SMN2
SCHEMBL9547960 0.60 LMNA (0.39) SMN1; SMN2
SCHEMBL8392292 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107098787-A A kind of ring-type enyne compounds and its synthetic method 三峡大学 2017-08-29 CN disclosed