Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28167083 | 0.90 | ABL1 (0.39) | ABL1RIN1SMN1; SMN2GAANPC1 | |
| SCHEMBL14252745 | 0.88 | SMN1; SMN2 (0.40) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| SCHEMBL3718701 | 0.85 | CA5A (0.54) | ABL1RIN1SMN1; SMN2GAANPC1 | |
| SCHEMBL28138436 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| SCHEMBL151254 | 0.83 | MAPT (0.40) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| SCHEMBL15056506 | 0.82 | ABL1 (0.45) | ABL1RIN1SMN1; SMN2GAANPC1 | |
| SCHEMBL5093436 | 0.81 | LMNA (0.41) | SMN1; SMN2GAANPC1RAB9AL3MBTL1 | |
| SCHEMBL15055428 | 0.80 | GAA (0.46) | ABL1RIN1SMN1; SMN2GAANPC1 | |
| SCHEMBL134808 | 0.79 | ABL1 (0.59) | ABL1RIN1SMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL137848 | 0.79 | MAPT (0.52) | ABL1RIN1SMN1; SMN2GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106995433-A | A kind of Ai Le replaces the preparation method of Buddhist nun | 湖南博奥德生物医药技术开发有限公司 | 2017-08-01 | — | — | CN | disclosed |