Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL732230 | 0.86 | NQO2 (0.50) | IDO1NQO2POLBGLSNAMPT | |
| SCHEMBL14987233 | 0.81 | GLS (0.50) | IDO1NQO2POLBGLSNAMPT | |
| SCHEMBL16798316 | 0.81 | NQO2 (0.50) | IDO1NQO2ALDH1A1POLBGLS | |
| SCHEMBL9985225 | 0.81 | NQO2 (0.52) | IDO1NQO2POLBGLSNAMPT | |
| SCHEMBL27832827 | 0.80 | NQO2 (0.51) | IDO1NQO2POLBGLSNAMPT | |
| SCHEMBL572740 | 0.79 | IDO1 (0.60) | IDO1ALDH1A1TAAR1NAMPTCTSK | |
| SCHEMBL320558 | 0.79 | NQO2 (0.50) | IDO1NQO2POLBNAMPTKDM4E | |
| SCHEMBL69058 | 0.78 | NQO2 (0.62) | IDO1NQO2POLBNAMPTKDM4E | |
| SCHEMBL16787407 | 0.78 | POLB (0.62) | IDO1NQO2ALDH1A1POLBNAMPT | |
| SCHEMBL31505839 | 0.78 | NQO2 (0.62) | IDO1NQO2POLBNAMPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106977425-B | Hydroxamic acid derivs and the preparation method and application thereof with dnmt rna and histon deacetylase (HDAC) inhibitory activity | 清华大学深圳研究生院 | 2019-07-19 | — | — | CN | disclosed |
| CN-106977425-A | Hydroxamic acid derivs with dnmt rna and histon deacetylase (HDAC) inhibitory activity and preparation method and application | 清华大学深圳研究生院 | 2017-07-25 | — | — | CN | disclosed |