Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.60 |
| ▸ | NAMPT | P43490 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CTSK | P43235 | 3/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL8529443 | 0.94 | CTSK (0.57) | IDO1NAMPTNPC1RAB9AMAPT | |
| SCHEMBL25048413 | 0.91 | CA1 (0.60) | IDO1NAMPTNPC1RAB9AMAPT | |
| SCHEMBL18800977 | 0.91 | NAMPT (0.58) | IDO1NAMPTNPC1RAB9AMAPT | |
| SCHEMBL8399561 | 0.91 | IDO1 (0.55) | IDO1NAMPTNPC1RAB9AMAPT | |
| SCHEMBL4583683 | 0.90 | POLB (0.65) | IDO1NPC1RAB9ACTSKGAA | |
| SCHEMBL8171226 | 0.90 | RAB9A (0.68) | NAMPTNPC1RAB9AMAPTTAAR1 | |
| SCHEMBL8573380 | 0.90 | SIGMAR1 (0.54) | IDO1NAMPTNPC1RAB9AMAPT | |
| SCHEMBL4961185 | 0.89 | SIGMAR1 (0.62) | IDO1GAASIGMAR1ALDH1A1CYP3A4 | |
| SCHEMBL13886599 | 0.88 | EPHX2 (0.59) | IDO1NAMPTNPC1RAB9ACTSK | |
| SCHEMBL4446760 | 0.88 | MEN1 (0.55) | IDO1NAMPTNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115477626-B | N-substituted phenyl sulfonamide compound and application thereof | 上海璃道医药科技有限公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-113939516-B | Methods and compositions for targeting protein degradation | 珃诺生物医药科技(杭州)有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-117529474-A | N-substituted phenyl sulfonamide compound and application thereof | 上海璃道医药科技有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-116457023-A | antibody-TLR agonist conjugates, methods and uses thereof | AMBRX公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-110914238-B | Compounds as antibiotics | 安塔比奥公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-111051309-B | Triazolotriazine derivatives useful as A2A receptor antagonists | 浙江春禾医药科技有限公司 | 2023-05-26 | — | — | CN | disclosed |
| WO-2023078410-A1 | COMPOUND HAVING ACTIVITY OF DEGRADING GSPT1 AND APPLICATION THEREOF | 上海美志医药科技有限公司 | 2023-05-11 | — | — | WO | disclosed |
| CN-113939516-A | Methods and compositions for targeted protein degradation | 珃诺生物医药科技(杭州)有限公司 | 2022-01-14 | — | — | CN | disclosed |
| CN-113924123-A | Methods and compositions for targeted protein degradation | 珃诺生物医药科技(杭州)有限公司 | 2022-01-11 | — | — | CN | disclosed |
| CN-113480524-A | Alkaloid hamacanthins series derivatives, and preparation method and application thereof | 河北工业大学 | 2021-10-08 | — | — | CN | disclosed |
| EP-0815105-A1 | HETEROCYCLIC SUBSTITUTED PIPERAZINONE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | HOECHST MARION ROUSSEL, INC. (US) | 1998-01-07 | — | — | EP | disclosed |
| EP-0812205-A1 | ANTITHROMBOTIC AZACYCLOALKYLALKANOYL PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1997-12-17 | — | — | EP | disclosed |
| EP-0764163-A1 | TACHYKININ (NK 1) RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1997-03-26 | — | — | EP | disclosed |
| US-5610176-A | USEFUL IN TREATING ASTHMA, MULTIPLE SCLEROSIS, RHEUMATOID ARTHRITIS, PAIN, MIGRAINE AND EMESIS | WARNER-LAMBERT COMPANY (US) | 1997-03-11 | — | — | US | disclosed |
| WO-1996028441-A1 | HETEROCYCLIC SUBSTITUTED PIPERAZINONE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-09-19 | — | — | WO | disclosed |
| WO-1995033744-A1 | TACHYKININ (NK1) RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1995-12-14 | — | — | WO | disclosed |
| WO-1995010295-A1 | ANTITHROMBOTIC AZACYCLOALKYLALKANOYL PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1995-04-20 | — | — | WO | disclosed |
| EP-0435887-A1 | RENIN INHIBITORY PEPTIDES CONTAINING MALEAMIDE SUBSTITUENTS | THE UPJOHN COMPANY (US) | 1991-07-10 | — | — | EP | disclosed |
| WO-1990003389-A1 | RENIN INHIBITORY PEPTIDES CONTAINING MALEAMIDE SUBSTITUENTS | THE UPJOHN COMPANY (US) | 1990-04-05 | — | — | WO | disclosed |
| CN-85101512-A | PROCESS FOR PREPARING CARBAMIC ACID DERIVATIVES | — | 1987-01-17 | — | — | CN | disclosed |