Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31303707 | 0.87 | ALOX15 (0.59) | ALOX15NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2817780 | 0.87 | ALOX15 (0.59) | ALOX15NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2817244 | 0.85 | ALOX15 (0.62) | ALOX15NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2563160 | 0.84 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL28040080 | 0.83 | ALOX15 (0.55) | ALOX15ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL25299267 | 0.83 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL2817317 | 0.83 | NPC1 (0.50) | ALOX15NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2815127 | 0.83 | ALOX15 (0.59) | ALOX15NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL357406 | 0.82 | PTGS1 (0.64) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL2815756 | 0.82 | ALOX15 (0.65) | ALOX15LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10869822-B2 | Compositions for treatment of dermatological diseases and conditions and methods of use thereof | DermaMedics, LLC (US) | 2020-12-22 | — | — | US | disclosed |
| US-20180235859-A1 | Compositions for Treatment of Dermatological Diseases and Conditions and Methods of Use Thereof | DermaMedics, LLC | 2018-08-23 | — | — | US | disclosed |
| US-9980887-B2 | Compositions for use in treatment of hyperpigmentation and methods of use thereof | DermaMedics, LLC (US) | 2018-05-29 | — | — | US | disclosed |
| EP-3238696-A1 | METHODS AND COMPOSITIONS FOR TREATING DERMATOLOGICAL DISEASES AND CONDITIONS | Therametics, Llc (US) | 2017-11-01 | — | — | EP | disclosed |
| US-9622950-B2 | Compositions for use in treatment of dermatological diseases and conditions | DermaMedics, LLC (US) | 2017-04-18 | — | — | US | disclosed |
| US-9616006-B2 | Methods and compositions for treating dermatological diseases and conditions | DermaMedics, LLC (US) | 2017-04-11 | — | — | US | disclosed |
| US-20160346180-A1 | Compositions for Use in Treatment of Dermatological Diseases and Conditions and Methods of Use Thereof | DERMAMEDICS LLC (US) | 2016-12-01 | — | — | US | disclosed |
| US-20130289006-A1 | COMPOSITIONS FOR TREATING HYPERPIGMENTATION AND METHODS OF USE THEREOF | DermaMedics, LLC | 2013-10-31 | — | — | US | disclosed |
| US-20130280195-A1 | COMPOSITIONS FOR USE IN TREATMENT OF DERMATOLOGICAL DISEASES AND CONDITIONS AND METHODS OF USE THEREOF | DermaMedics, LLC | 2013-10-24 | — | — | US | disclosed |
| US-20130281411-A1 | COMPOSITIONS FOR TREATING INFLAMMATORY DERMATOLOGICAL DISEASES AND CONDITIONS AND METHODS OF USE THEREOF | DermaMedics, LLC | 2013-10-24 | — | — | US | disclosed |
| US-20130274231-A1 | COMPOSITIONS FOR USE IN TREATMENT OF DERMATOLOGICAL DISEASES AND CONDITIONS | DermaMedics, LLC | 2013-10-17 | — | — | US | disclosed |
| EP-2244690-A1 | METHODS AND COMPOSITIONS FOR TREATING DERMATOLOGICAL DISEASES AND CONDITIONS | Therametics, Llc (US) | 2010-11-03 | — | — | EP | disclosed |
| US-20100249244-A1 | METHODS AND COMPOSITIONS FOR TREATING DERMATOLOGICAL DISEASES AND CONDITIONS | THERAMETICS, LLC | 2010-09-30 | — | — | US | disclosed |
| WO-2009049172-A1 | METHODS AND COMPOSITIONS FOR TREATING DERMATOLOGICAL DISEASES AND CONDITIONS | THERAMETICS, LLC (US) | 2009-04-16 | — | — | WO | disclosed |