Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.50 |
| ▸ | TUBB | P07437 | 2/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.50 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.50 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.50 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.50 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040077 | 0.85 | TUBB4A (0.54) | ALOX15KMT2AMEN1TUBB4ATUBB | |
| SCHEMBL28040067 | 0.83 | ADRB2 (0.53) | ALOX15KMT2AMEN1TUBB4ATUBB | |
| SCHEMBL2816724 | 0.83 | ALOX15 (0.61) | ALOX15KMT2AMEN1KDM4ETP53 | |
| SCHEMBL28040730 | 0.80 | EPHX2 (0.53) | ALOX15KMT2AMEN1TUBB4ATUBB | |
| SCHEMBL28040073 | 0.79 | KMT2A (0.57) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL28040081 | 0.76 | KMT2A (0.48) | KMT2AMEN1TUBB4ATUBBTUBA3C | |
| SCHEMBL891511 | 0.76 | PTGS1 (0.71) | ALOX15KMT2AMEN1KDM4ETP53 | |
| SCHEMBL28040076 | 0.76 | KMT2A (0.61) | KMT2AMEN1TUBB4ATUBBTUBA3C | |
| SCHEMBL20696534 | 0.76 | TUBB4A (0.74) | KMT2AMEN1TUBB4ATUBBTUBA3C | |
| SCHEMBL29689431 | 0.76 | TUBB4A (0.74) | KMT2AMEN1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175262-A | Chrysotoxine bibenzyl derivative and preparation method and application thereof | UNIV CHINA PHARMA | 2015-12-23 | — | — | CN | claimed |
| CN-105175262-A | Chrysotoxine bibenzyl derivative and preparation method and application thereof | UNIV CHINA PHARMA | 2015-12-23 | — | — | CN | disclosed |