Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38009 | 0.87 | — | — | |
| Alcohol SCHEMBL28946691 | 0.85 | — | — | |
| SCHEMBL8719772 | 0.85 | — | — | |
| Ether SCHEMBL20704371 | 0.84 | — | — | |
| SCHEMBL5311500 | 0.83 | HTR1A (0.33) | HTR1AHTR1DHTR1B | |
| Methylene Chloride SCHEMBL27497108 | 0.83 | — | — | |
| SCHEMBL27842381 | 0.81 | — | — | |
| SCHEMBL5227809 | 0.78 | — | — | |
| SCHEMBL3478039 | 0.77 | — | — | |
| SCHEMBL5960796 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104812748-B | Pyrazoline GPR40 conditioning agents | 百时美施贵宝公司 | 2017-10-24 | — | — | CN | disclosed |
| CN-104918935-B | dihydropyrazole GPR40 modulators | 百时美施贵宝公司 | 2017-07-28 | — | — | CN | disclosed |