Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | FLT3 | P36888 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4555728 | 0.90 | FLT3 (0.55) | CDK2FLT3ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL2819888 | 0.81 | FLT3 (0.54) | CDK2FLT3ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL27776125 | 0.80 | NTRK1 (0.50) | ALDH1A1MEN1KMT2APKMNAMPT | |
| SCHEMBL28782786 | 0.80 | NTRK1 (0.48) | ROCK1ALDH1A1NPC1SMN1; SMN2MAPT | |
| SCHEMBL4556320 | 0.79 | FLT3 (0.46) | ROCK1CDK2FLT3ALDH1A1NPC1 | |
| SCHEMBL2815480 | 0.78 | NTRK1 (0.53) | CDK2FLT3ALDH1A1NPC1RAB9A | |
| SCHEMBL27796823 | 0.78 | NTRK1 (0.62) | CDK2FLT3ALDH1A1NPC1RAB9A | |
| SCHEMBL4442225 | 0.78 | SMN1; SMN2 (0.54) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2813712 | 0.78 | KMT2A (0.67) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2818030 | 0.78 | NTRK1 (0.52) | CDK2FLT3ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249123-A1 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249123-A1 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | FSHR, GNRHR, SHBG | ROCK1 2031/4885CDK2 236/4885FLT3 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.