Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28044195 | 0.82 | CES2 (0.56) | CES2CES1PTPN1HTTNPSR1 | |
| SCHEMBL5201425 | 0.77 | CES2 (0.54) | CES2CES1PTPN1HTTNPSR1 | |
| SCHEMBL9508524 | 0.73 | CES2 (0.48) | CES2CES1PTPN1HTTNPSR1 | |
| SCHEMBL11328573 | 0.73 | HTT (0.51) | CES2CES1PTPN1HTTNPSR1 | |
| SCHEMBL743549 | 0.72 | CES2 (0.58) | CES2CES1PTPN1HTTNPSR1 | |
| SCHEMBL20492515 | 0.72 | CES2 (0.52) | CES2CES1PTPN1HTTNPSR1 | |
| Hydrochloric Acid SCHEMBL28901385 | 0.71 | HTT (0.50) | CES2CES1PTPN1HTTNPSR1 | |
| Formic Acid SCHEMBL28853289 | 0.71 | CES2 (0.56) | CES2CES1PTPN1HTTNPSR1 | |
| SCHEMBL226605 | 0.71 | CES2 (0.56) | CES2CES1PTPN1HTTNPSR1 | |
| SCHEMBL4031476 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106967020-A | A kind of synthetic method of 2 furoyl hydrazine | 重庆丽澄环保科技有限公司 | 2017-07-21 | — | — | CN | disclosed |