Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL743549 | 0.83 | CES2 (0.58) | CES2CES1PTPN1HTTNPSR1 | |
| SCHEMBL226605 | 0.82 | CES2 (0.56) | CES2CES1PTPN1HTTNPSR1 | |
| SCHEMBL11465945 | 0.81 | CES2 (0.50) | CES2CES1PTPN1HTTNPSR1 | |
| SCHEMBL11465943 | 0.81 | CES2 (0.50) | CES2CES1PTPN1HTTNPSR1 | |
| SCHEMBL9508524 | 0.79 | CES2 (0.48) | CES2CES1PTPN1HTTNPSR1 | |
| SCHEMBL10724442 | 0.78 | RAB9A (0.53) | CES2CES1PTPN1HTTNPSR1 | |
| SCHEMBL2306849 | 0.77 | CES2 (0.55) | CES2CES1PTPN1HTTNPSR1 | |
| Hydrochloric Acid SCHEMBL11684928 | 0.77 | CES2 (0.50) | CES2CES1PTPN1HTTNPSR1 | |
| SCHEMBL28167448 | 0.77 | CES2 (0.50) | CES2CES1PTPN1HTTNPSR1 | |
| SCHEMBL1106996 | 0.77 | CES2 (0.50) | CES2CES1PTPN1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070265231-A1 | Hydrazide Compounds for Combating Animal Pests | BASF AKTIENGESELLSCHAFT (DE) | 2007-11-15 | — | — | US | disclosed |
| EP-1819224-A1 | HYDRAZIDE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006058730-A1 | HYDRAZIDE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2006-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265231-A1 | Hydrazide Compounds for Combating Animal Pests | HRH4, CBR3, HRH2 | CES2 2048/4885CES1 1952/4885PTPN1 1489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.