Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10068809 | 0.81 | PARP15 (0.49) | F2PARP15PARP10PARP2NR1H4 | |
| SCHEMBL27819862 | 0.79 | CA12 (0.44) | KMT2AMEN1 | |
| SCHEMBL14813011 | 0.77 | WDR5 (0.48) | F2PARP15PARP10PARP2WDR5 | |
| SCHEMBL27968606 | 0.76 | PDE4B (0.42) | PARP15PARP10PARP2PDE4APDE4B | |
| SCHEMBL21817404 | 0.76 | KAT6A (0.52) | F2PARP15PARP10PARP2NR1H4 | |
| SCHEMBL10068810 | 0.76 | NR1H4 (0.50) | F2PARP15PARP10PARP2NR1H4 | |
| SCHEMBL30056075 | 0.76 | KAT6A (0.52) | F2PARP15PARP10PARP2NR1H4 | |
| SCHEMBL14164999 | 0.75 | PARP15 (0.47) | F2PARP15PARP10PARP2ADORA2B | |
| SCHEMBL16396797 | 0.75 | NOTUM (0.46) | F2PARP15PARP10PARP2ADORA2B | |
| SCHEMBL10068795 | 0.74 | WDR5 (0.44) | F2PARP15PARP10PARP2ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106946848-A | It is used as the derivative of the pyridyl alkyl alcohol of 1 phenyl 2 of phosphodiesterase inhibitors | 奇斯药制品公司 | 2017-07-14 | — | — | CN | disclosed |