Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL531446 | 0.92 | MEN1 (0.57) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL22323298 | 0.92 | MEN1 (0.57) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL4473656 | 0.92 | MEN1 (0.57) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL9470043 | 0.83 | KMT2A (0.54) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL2393243 | 0.76 | MEN1 (0.54) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL15209971 | 0.76 | LDHA (0.49) | MEN1KMT2AALDH1A1L3MBTL1PSEN1 | |
| SCHEMBL1701279 | 0.75 | KMT2A (0.76) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL4662517 | 0.73 | TSHR (0.45) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL1371851 | 0.73 | TSHR (0.45) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL1371848 | 0.73 | TSHR (0.45) | MEN1KMT2AALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107080747-A | Glucosylceramide synthase inhibitor | 建新公司 | 2017-08-22 | — | — | CN | disclosed |