Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 16/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 16/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 9/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 9/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621978 | 0.79 | G6PD (0.50) | — | |
| SCHEMBL17297895 | 0.74 | CHRNB2 (0.62) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL16906432 | 0.73 | GAA (0.66) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL17166193 | 0.72 | CHRNB2 (0.44) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL26799664 | 0.71 | CHRNB2 (0.59) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL24783890 | 0.70 | CHRNB2 (0.55) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL17297893 | 0.70 | CHRNB2 (0.57) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL30047447 | 0.70 | CHRNB2 (0.55) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL17691522 | 0.70 | CHRNB2 (0.57) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL20858748 | 0.69 | CHRNB2 (0.62) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074775-A | The preparation method of 3 (base of 3 chlorine 1H pyrazoles 1) pyridines | 美国陶氏益农公司 | 2017-08-18 | — | — | CN | disclosed |