Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 3/20 | 0.39 |
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | RARG | P13631 | 3/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2761577 | 0.86 | HSD11B1 (0.38) | HSD11B1ALOX5AP | |
| Terephthalic Acid SCHEMBL9341496 | 0.74 | ALOX5AP (0.56) | HSD11B1MEN1KMT2ARARARARB | |
| SCHEMBL3688895 | 0.70 | HSD11B1 (0.35) | HSD11B1 | |
| Terephthalic Acid SCHEMBL3691392 | 0.66 | TSHR (0.92) | TP53TSHRSRD5A2ALDH1A1ALOX15 | |
| SCHEMBL8733039 | 0.65 | HSD11B1 (0.37) | HSD11B1ALOX5AP | |
| SCHEMBL422261 | 0.65 | NPC1 (0.56) | EPHX2MEN1KMT2ATP53RARA | |
| SCHEMBL21221605 | 0.65 | HSD11B1 (0.38) | HSD11B1ALOX5AP | |
| SCHEMBL22441207 | 0.64 | EPHX2 (0.68) | EPHX2MEN1KMT2ARARARARB | |
| SCHEMBL23558947 | 0.64 | ALOX5AP (0.45) | HSD11B1ALOX5APKDM4E | |
| Terephthalic Acid SCHEMBL28392831 | 0.63 | TSHR (0.86) | TP53TSHRSRD5A2ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107073867-B | Stacking pipe | 宇部兴产株式会社 | 2019-08-16 | — | — | CN | disclosed |
| CN-109311259-A | Laminated tube | 宇部兴产株式会社 | 2019-02-05 | — | — | CN | disclosed |
| CN-105517789-B | laminated tube | 宇部兴产株式会社 | 2017-10-17 | — | — | CN | disclosed |
| CN-107148451-A | Polyamide composition and molded article formed from same | 宇部兴产株式会社 | 2017-09-08 | — | — | CN | disclosed |
| CN-107073867-A | Stacking pipe | 宇部兴产株式会社 | 2017-08-18 | — | — | CN | disclosed |