SCHEMBL2761577

SCHEMBL2761577

O=C(O)C1(C(=O)O)CC2CCC1C2

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 3/20 0.38
ALOX5AP P20292 1/20 0.33
PKM P14618 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27660399 0.98 HSD11B1 (0.37) HSD11B1ALOX5AP
SCHEMBL28770909 0.98 HSD11B1 (0.37) HSD11B1ALOX5AP
Terephthalic Acid SCHEMBL28169171 0.86 HSD11B1 (0.40) HSD11B1ALOX5AP
SCHEMBL27948270 0.83 HSD11B1 (0.33) HSD11B1L3MBTL1
SCHEMBL3688895 0.82 HSD11B1 (0.35) HSD11B1
SCHEMBL27603731 0.80 HSD11B1 (0.34) HSD11B1
SCHEMBL8733039 0.76 HSD11B1 (0.37) HSD11B1ALOX5AP
SCHEMBL16904311 0.74 HSD11B1 (0.40) HSD11B1ALOX5AP
SCHEMBL3733593 0.74 SLC6A4 (0.41) HSD11B1
SCHEMBL202772 0.74 SLC6A4 (0.41) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010138330-A2 SCRATCH RESISTANT POLYPROPYLENE BASF PERFORMANCE PRODUCTS LLC (US) 2010-12-02 WO claimed
WO-2023113260-A1 PHOSPHOROUS MONOMER OR OLIGOMER, POLYESTER RESIN COMPRISING SAME, AND THERMOPLASTIC RESIN COMPOSITION 주식회사 엘지화학 2023-06-22 WO disclosed
WO-2023059059-A1 PHOSPHOROUS OLIGOMER, POLYESTER RESIN AND THERMOPLASTIC RESIN COMPOSITION COMPRISING SAME 주식회사 엘지화학 2023-04-13 WO disclosed
CN-110785442-B High melt strength polypropylene with high stiffness and clarity 埃克森美孚化学专利公司 2022-05-13 CN disclosed
CN-109721699-B Polylactic acid copolyester and preparation method thereof, and biaxially stretched polylactic acid copolyester film and preparation method thereof 中国石油化工股份有限公司 2022-03-29 CN disclosed
CN-109721976-B Polylactic acid composition and preparation method thereof, and biaxially stretched polylactic acid film and preparation method thereof 中国石油化工股份有限公司 2021-12-21 CN disclosed
CN-112805322-A Polypropylene for films 埃克森美孚化学专利公司 2021-05-14 CN disclosed
CN-108472943-B Multilayer structure 三菱瓦斯化学株式会社 2021-04-06 CN disclosed
US-10654986-B2 Surface treated filler material product for alpha-nucleation of polyolefins OMYA INTERNATIONAL AG (CH) 2020-05-19 US disclosed
CN-110785442-A High melt strength polypropylene with high stiffness and clarity 埃克森美孚化学专利公司 2020-02-11 CN disclosed
WO-2019194117-A1 POLYESTER RESIN COMPOSITION 三菱瓦斯化学株式会社 2019-10-10 WO disclosed
US-20180163014-A1 SURFACE TREATED FILLER MATERIAL PRODUCT FOR ALPHA-NUCLEATION OF POLYOLEFINS OMYA INTERNATIONAL AG (CH) 2018-06-14 US disclosed
EP-2500348-B1 PHOSPHOLIPID DERIVATIVE AND PH-RESPONSIVE LIPOSOMES NOF CORP (JP) 2017-08-23 EP disclosed
EP-2838948-A1 NUCLEATING AGENTS FOR POLYPROPYLENE AND PROPYLENE COPOLYMERS Technische Universiteit Eindhoven (NL) 2015-02-25 EP disclosed
CN-102844365-B Granulated resin additive composition ADEKA CORP 2014-12-03 CN disclosed
WO-2013156565-A1 NUCLEATING AGENTS FOR POLYPROPYLENE AND PROPYLENE COPOLYMERS TECHNISCHE UNIVERSITEIT EINDHOVEN (NL) 2013-10-24 WO disclosed
US-8445712-B2 Phospholipid derivative and pH-responsive liposomes NOF CORPORATION (JP) 2013-05-21 US disclosed
US-20120258165-A1 PHOSPHOLIPID DERIVATIVE AND PH-RESPONSIVE LIPOSOMES OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION (JP) 2012-10-11 US disclosed
EP-2500348-A1 PHOSPHOLIPID DERIVATIVE AND PH-RESPONSIVE LIPOSOMES NOF Corporation (JP) 2012-09-19 EP disclosed
WO-2010138330-A2 SCRATCH RESISTANT POLYPROPYLENE BASF PERFORMANCE PRODUCTS LLC (US) 2010-12-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120258165-A1 PHOSPHOLIPID DERIVATIVE AND PH-RESPONSIVE LIPOSOMES PHOSPHO1, SGMS1, PLTP HSD11B1 3659/4885ALOX5AP 337/4885PKM 2617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.