Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 13/20 | 0.58 |
| ▸ | NPC1 | O15118 | 11/20 | 0.58 |
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28170029 | 1.00 | KMT2A (0.63) | KMT2AMEN1RAB9ANPC1GAA | |
| SCHEMBL28170025 | 0.83 | RAB9A (0.68) | KMT2AMEN1RAB9ANPC1GAA | |
| SCHEMBL28170026 | 0.83 | RAB9A (0.68) | KMT2AMEN1RAB9ANPC1GAA | |
| SCHEMBL28170571 | 0.78 | RAB9A (0.52) | KMT2AMEN1RAB9ANPC1GAA | |
| SCHEMBL28170572 | 0.78 | RAB9A (0.52) | KMT2AMEN1RAB9ANPC1GAA | |
| SCHEMBL17560759 | 0.76 | KMT2A (0.69) | KMT2AMEN1RAB9ANPC1GAA | |
| SCHEMBL17560761 | 0.76 | KMT2A (0.69) | KMT2AMEN1RAB9ANPC1GAA | |
| SCHEMBL13381008 | 0.76 | MEN1 (0.48) | KMT2AMEN1RAB9ANPC1GAA | |
| SCHEMBL11124641 | 0.75 | RAB9A (0.97) | KMT2AMEN1RAB9ANPC1GAA | |
| SCHEMBL14832820 | 0.75 | RAB9A (0.97) | KMT2AMEN1RAB9ANPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107106524-A | Methods for treating protozoal infections | 尼奥酷里私人有限公司 | 2017-08-29 | — | — | CN | disclosed |