Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28170368 | 0.93 | ALDH1A1 (0.56) | KMT2AMAPTALDH1A1POLBTSHR | |
| SCHEMBL13479827 | 0.92 | MAPT (0.54) | KMT2AMAPTALDH1A1POLBTSHR | |
| SCHEMBL25239845 | 0.81 | ALDH1A1 (0.59) | KMT2AALDH1A1GAALMNAATM | |
| SCHEMBL20746614 | 0.80 | KMT2A (0.53) | KMT2AMAPTALDH1A1POLBTSHR | |
| SCHEMBL4907232 | 0.78 | ALDH1A1 (0.76) | KMT2AMAPTALDH1A1POLBTSHR | |
| SCHEMBL5499660 | 0.77 | KMT2A (0.49) | KMT2AMAPTALDH1A1POLBTSHR | |
| SCHEMBL5499657 | 0.77 | KMT2A (0.49) | KMT2AMAPTALDH1A1POLBTSHR | |
| SCHEMBL5873315 | 0.76 | ALDH1A1 (0.61) | KMT2AMAPTALDH1A1POLBTSHR | |
| SCHEMBL13479828 | 0.76 | KMT2A (0.52) | KMT2AMAPTALDH1A1POLBGAA | |
| SCHEMBL28190066 | 0.75 | MAPT (0.59) | KMT2AMAPTALDH1A1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295726-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-105764883-B | Thermoplastic polymer composition | 美利肯公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-105764971-B | Thermoplastic polymer composition | 美利肯公司 | 2018-04-06 | — | — | CN | disclosed |
| CN-105745264-B | Thermoplastic polymer composition | 美利肯公司 | 2018-03-13 | — | — | CN | disclosed |
| CN-105745189-B | Thermoplastic polymer composition | 美利肯公司 | 2017-11-21 | — | — | CN | disclosed |