Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.76 |
| ▸ | MAPT | P10636 | 4/20 | 0.76 |
| ▸ | POLB | P06746 | 2/20 | 0.76 |
| ▸ | TSHR | P16473 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5809526 | 0.86 | ALDH1A1 (1.00) | ALDH1A1KMT2AMAPTPOLBTSHR | |
| SCHEMBL29102460 | 0.86 | ALDH1A1 (0.70) | ALDH1A1KMT2AMAPTPOLBTSHR | |
| SCHEMBL6269137 | 0.86 | ALDH1A1 (0.70) | ALDH1A1KMT2AMAPTPOLBTSHR | |
| SCHEMBL27509048 | 0.85 | KMT2A (0.68) | ALDH1A1KMT2AMAPTPOLBTSHR | |
| SCHEMBL158309 | 0.85 | KMT2A (0.68) | ALDH1A1KMT2AMAPTPOLBTSHR | |
| SCHEMBL11146599 | 0.85 | ALDH1A1 (0.96) | ALDH1A1KMT2AMAPTPOLBTSHR | |
| SCHEMBL1107202 | 0.85 | ALDH1A1 (0.68) | ALDH1A1KMT2AMAPTPOLBTSHR | |
| SCHEMBL3035584 | 0.84 | ALDH1A1 (0.67) | ALDH1A1KMT2AMAPTPOLBTSHR | |
| SCHEMBL9150262 | 0.83 | ALDH1A1 (0.66) | ALDH1A1KMT2AMAPTPOLBTSHR | |
| SCHEMBL7645360 | 0.83 | ALDH1A1 (0.66) | ALDH1A1KMT2AMAPTPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509941-A2 | N-ACYLATED HYDROXYLAMINE DERIVATIVES AND O-ACYLATED HYDROXYLAMINE DERIVATIVES | The Johns Hopkins University (US) | 2012-10-17 | — | — | EP | disclosed |
| US-20080183007-A1 | Process For the Preparation of Alkyl Phosphinic Acids | ASTRAZENECA AB (SE) | 2008-07-31 | — | — | US | disclosed |
| EP-1799695-A1 | NEW PROCESS FOR THE PREPARATION OF ALKYL PHOSPHINIC ACIDS | AstraZeneca AB (SE) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006038870-A1 | NEW PROCESS FOR THE PREPARATION OF ALKYL PHOSPHINIC ACIDS | ASTRAZENECA AB (SE) | 2006-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080183007-A1 | Process For the Preparation of Alkyl Phosphinic Acids | PPIP5K2, AGPS, ITPA | ALDH1A1 2377/4885KMT2A 1758/4885MAPT 4798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.