2-Ethoxyethanol

2-Ethoxyethanol

SCHEMBL28170477

CCOCCO.OC(F)(C(F)F)C(F)(F)F

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.54
NR1H2 P55055 1/20 0.35
NR1H3 Q13133 1/20 0.35
TSHR P16473 2/20 0.34
MAPK1 P28482 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
THRB P10828 1/20 0.31
HTT P42858 1/20 0.31
MAPT P10636 1/20 0.31
CES1 P23141 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL28860658 0.86 CES1 (0.31) CES1
Butoxyethanol SCHEMBL28535738 0.84 TSHR (0.59) ALDH1A1NR1H2NR1H3TSHRMAPK1
Tetraethylene Glycol SCHEMBL28079853 0.81 MEN1 (0.38) ALDH1A1NR1H2NR1H3TSHRMAPK1
2-Methoxyethanol SCHEMBL28901932 0.80
Alcohol SCHEMBL28291903 0.79 ALDH1A1 (0.33) ALDH1A1TSHR
2-Ethoxyethanol SCHEMBL5570314 0.74 ALDH1A1 (0.78) ALDH1A1TSHRMAPK1MEN1KMT2A
Butyl Alcohol SCHEMBL16616621 0.74 ALDH1A1 (0.48) ALDH1A1TSHRMEN1KMT2ACES1
2-Ethoxyethanol SCHEMBL11024472 0.73 ALDH1A1 (1.00) ALDH1A1TSHRMAPK1MEN1KMT2A
2-Ethoxyethanol SCHEMBL9547497 0.73 ALDH1A1 (1.00) ALDH1A1TSHRMAPK1MEN1KMT2A
2-Ethoxyethanol SCHEMBL9432157 0.73 ALDH1A1 (1.00) ALDH1A1TSHRMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107163254-A A kind of preparation method and applications of solvent-borne type hydro-oleophobicity fluorohydrocarbon base silicones 陕西科技大学 2017-09-15 CN disclosed