Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 3/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30586448 | 1.00 | NT5E (0.36) | NT5EJAK2NTRK1RETMET | |
| SCHEMBL30586445 | 0.79 | NT5E (0.41) | NT5ECDK8ACVR1BACE1HSP90AA1 | |
| SCHEMBL5833184 | 0.78 | BACE1 (0.55) | NT5ECDK8ACVR1BACE1KDM4E | |
| SCHEMBL29612766 | 0.73 | ALDH1A1 (0.46) | NT5ECDK2ADORA2AADORA1KDM4E | |
| SCHEMBL30586443 | 0.73 | BACE1 (0.65) | NT5EBACE1CCNA2CDK2KDM4E | |
| SCHEMBL30586444 | 0.73 | NR4A2 (0.46) | NT5EJAK2NTRK1RETCDK8 | |
| SCHEMBL10967442 | 0.73 | BACE1 (0.65) | NT5EBACE1CCNA2CDK2KDM4E | |
| SCHEMBL29456173 | 0.73 | NT5E (0.54) | NT5EMAPK8MAPK9BACE1HSP90AA1 | |
| SCHEMBL20480626 | 0.73 | ALDH1A1 (0.46) | NT5ECDK2ADORA2AADORA1KDM4E | |
| SCHEMBL30503643 | 0.73 | LMNA (0.54) | BACE1HSP90AA1HSP90AB1KDM4EPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074814-A | Glucose transport inhibitor | 拜耳制药股份公司 | 2017-08-18 | — | — | CN | disclosed |