Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALOX15B | O15296 | 3/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28173706 | 0.91 | L3MBTL1 (0.53) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| Benzene SCHEMBL20549155 | 0.91 | L3MBTL1 (0.53) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9067047 | 0.85 | CYP3A4 (0.44) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8797095 | 0.84 | FYN (0.39) | L3MBTL1CYP3A4SMN1; SMN2HRH1HRH3 | |
| SCHEMBL8700995 | 0.83 | TSHR (0.42) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1046097 | 0.77 | SMO (0.45) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8609231 | 0.75 | CYP17A1 (0.43) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL10611050 | 0.74 | CALM1 (0.44) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9441365 | 0.72 | PDE4A (0.48) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL22290333 | 0.72 | CYP3A4 (0.46) | L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104797585-B | Aminoimidazopyridazines | 拜耳医药股份公司 | 2017-08-15 | — | — | CN | disclosed |