SCHEMBL28173191

SCHEMBL28173191

CCNCCCO[Si](OOC)(OOC)OOC

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.41
MEN1 O00255 1/20 0.41
GLA P06280 1/20 0.41
KMT2A Q03164 1/20 0.41
CYP1A2 P05177 1/20 0.39
TSHR P16473 1/20 0.39
SAT1 P21673 3/20 0.37
KDM1A O60341 5/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27898945 0.86 TSHR (0.39) CYP2C19MEN1GLAKMT2ATSHR
SCHEMBL27527007 0.82 CA12 (0.41) CYP2C19MEN1KMT2ACYP1A2TSHR
SCHEMBL28049902 0.81 CA12 (0.41) CYP2C19MEN1KMT2ACYP1A2TSHR
SCHEMBL27323606 0.79 HTR1B (0.35)
SCHEMBL27994902 0.78 KDM4E (0.35)
SCHEMBL10929730 0.76 ADRB2 (0.36) TSHR
SCHEMBL18041144 0.76 CA12 (0.38) CYP2C19MEN1KMT2ACYP1A2TSHR
SCHEMBL28942186 0.72 THRB (0.36) MEN1KMT2ATSHR
SCHEMBL1348073 0.72 THRB (0.36) MEN1KMT2ATSHR
SCHEMBL2504827 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107531960-A Thermoplastic compounds and product SABIC环球技术有限责任公司 2018-01-02 CN disclosed
CN-107207802-A Polypropylene composition SABIC环球技术有限责任公司 2017-09-26 CN disclosed