Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.46 |
| ▸ | GRM5 | P41594 | 4/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542204 | 0.81 | BCHE (0.49) | ADORA2AEGLN2IDO1ALDH1A1MEN1 | |
| SCHEMBL9539492 | 0.81 | FGFR1 (0.46) | ADORA2AEGLN2IDO1CLK4ALDH1A1 | |
| SCHEMBL2816945 | 0.81 | FYN (0.50) | ADORA2ALMNAHSD17B10ADORA1ADORA3 | |
| SCHEMBL2817849 | 0.78 | ADORA2A (0.69) | ADORA2AADORA1 | |
| SCHEMBL2817811 | 0.78 | ADORA2A (0.64) | ALDH1A3ADORA2ACLK4ALDH1A1LMNA | |
| SCHEMBL9539655 | 0.78 | IDO1 (0.43) | ADORA2AIDO1ALDH1A1LMNAKDM4E | |
| SCHEMBL2818300 | 0.76 | ALDH1A1 (0.52) | ALDH1A3ADORA2ACFTRCLK4ALDH1A1 | |
| SCHEMBL10730849 | 0.76 | ALDH1A1 (0.42) | ADORA2AALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL2818740 | 0.75 | ADORA2A (0.58) | ADORA2AALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL9540820 | 0.75 | ADORA2A (0.58) | ALDH1A3ADORA2AALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249142-A1 | IMIDAZOL[1,2-alpha]QUINOXALINES AND DERIVATIVES FOR THE TREATMENT OF CANCERS | UNIVERSITE DE MONTPELLIER I | 2010-09-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249142-A1 | IMIDAZOL[1,2-alpha]QUINOXALINES AND DERIVATIVES FOR THE TREATMENT OF CANCERS | IDH3A, NRAS, KRAS | ALDH1A3 2225/4885ADORA2A 1818/4885GRM5 1775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.