Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539492 | 0.81 | FGFR1 (0.46) | IDO1ADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL9542204 | 0.81 | BCHE (0.49) | IDO1ADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL2816945 | 0.81 | FYN (0.50) | ADORA2AADORA1LMNAADORA3RAB9A | |
| SCHEMBL2817811 | 0.80 | ADORA2A (0.64) | ADORA2AADORA1KDM4EALDH1A1LMNA | |
| SCHEMBL2817465 | 0.78 | ALDH1A3 (0.51) | IDO1ADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL9539461 | 0.78 | NPC1 (0.58) | ADORA2AADORA1KDM4EALDH1A1LMNA | |
| SCHEMBL2818740 | 0.75 | ADORA2A (0.58) | ADORA2AADORA1KDM4EALDH1A1LMNA | |
| SCHEMBL9540820 | 0.75 | ADORA2A (0.58) | ADORA2AADORA1KDM4EALDH1A1LMNA | |
| SCHEMBL9538674 | 0.71 | KDM4E (0.39) | ADORA2AADORA1KDM4EALDH1A1LMNA | |
| SCHEMBL2815100 | 0.70 | ALDH1A1 (0.41) | IDO1ADORA2AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993004066-A1 | CERTAIN IMIDAZOQUINOXALINOLS; A NEW CLASS OF GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 1993-03-04 | — | — | WO | disclosed |