Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 14/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 12/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1954713 | 0.88 | FAAH (0.58) | FAAHTRPV1ALDH1A1RAB9AKDM4E | |
| SCHEMBL2722740 | 0.80 | CTSS (0.55) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8890541 | 0.79 | CTSS (0.54) | ALDH1A1 | |
| SCHEMBL10310649 | 0.78 | FAAH (0.49) | FAAHTRPV1ALDH1A1RAB9AKDM4E | |
| SCHEMBL19275676 | 0.77 | FAAH (0.59) | FAAHTRPV1ALDH1A1RAB9AKDM4E | |
| SCHEMBL30408248 | 0.77 | FAAH (0.59) | FAAHTRPV1ALDH1A1RAB9AKDM4E | |
| SCHEMBL21618459 | 0.77 | FAAH (0.59) | FAAHTRPV1ALDH1A1RAB9AKDM4E | |
| SCHEMBL5675472 | 0.77 | FAAH (0.72) | FAAHTRPV1ALDH1A1RAB9A | |
| SCHEMBL19275674 | 0.77 | FAAH (0.59) | FAAHTRPV1ALDH1A1RAB9AKDM4E | |
| SCHEMBL6245224 | 0.76 | FAAH (0.58) | FAAHTRPV1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108434149-A | For the regulated treatments of HSPC of Rb positive abnormal cell proliferations | G1治疗公司 | 2018-08-24 | — | — | CN | disclosed |
| CN-108283644-A | To the instantaneous protection of normal cell during chemotherapy | G1治疗公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-105407889-B | HSPC-sparing therapy for Rb-positive abnormal cell proliferation | G1治疗公司 | 2018-06-01 | — | — | CN | disclosed |
| CN-105473140-B | Transient protection of normal cells during chemotherapy | G1治疗公司 | 2018-04-10 | — | — | CN | disclosed |
| CN-107417691-A | Efficient anti-superfluous raw agent and anti-proliferative agent | G1治疗公司 | 2017-12-01 | — | — | CN | disclosed |