SCHEMBL28175286

SCHEMBL28175286

CCONc1ccc(C=O)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.38
GAA P10253 1/20 0.38
TSHR P16473 1/20 0.37
RAB9A P51151 5/20 0.36
NPC1 O15118 3/20 0.36
PKM P14618 1/20 0.36
KMT2A Q03164 3/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
LMNA P02545 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
EGFR P00533 1/20 0.32
POLB P06746 3/20 0.32
MEN1 O00255 2/20 0.32
GRIA1 P42261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27514231 0.78 POLB (0.46) ALDH1A1GAATSHRRAB9ANPC1
SCHEMBL6554556 0.77 ALDH1A1 (0.41) ALDH1A1GAATSHRRAB9ANPC1
SCHEMBL1248412 0.76 RAB9A (0.54) ALDH1A1GAATSHRRAB9ANPC1
SCHEMBL2766868 0.74 ALDH1A1 (0.45) ALDH1A1TSHRRAB9ANPC1PKM
SCHEMBL5810770 0.72 CYP1A2 (0.41) ALDH1A1GAARAB9ANPC1KMT2A
SCHEMBL27538511 0.72 ALDH1A1 (0.51) ALDH1A1GAATSHRRAB9ANPC1
SCHEMBL21367256 0.71 ALDH1A1 (0.47) ALDH1A1TSHRMAPT
SCHEMBL8096813 0.70 ALDH1A1 (0.41) ALDH1A1GAATSHRRAB9ANPC1
SCHEMBL3721962 0.70 ALDH1A1 (0.47) ALDH1A1GAATSHRKMT2ALMNA
SCHEMBL4460260 0.70 ALDH1A1 (0.50) ALDH1A1GAATSHRRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109574880-A A kind of fluorescence probe and its preparation method and application 华东理工大学 2019-04-05 CN disclosed
CN-108368058-A DOPANT, CHARGE TRANSFER SALT AND ORGANIC ELECTRONIC DEVICE 剑桥显示技术有限公司 2018-08-03 CN disclosed
CN-108292713-A Charge transfer salt, electronic device and forming method thereof 剑桥显示技术有限公司 2018-07-17 CN disclosed
CN-107641121-A Fluorescent probe and preparation method and application thereof 华东理工大学 2018-01-30 CN disclosed
CN-107106708-A MRI Imaging of Amyloid Plaques Using Liposomes 德克萨斯州儿童医院 2017-08-29 CN disclosed