Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 3/20 | 0.49 |
| ▸ | GABRD | O14764 | 3/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.49 |
| ▸ | GABRE | P78334 | 3/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.49 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19461871 | 0.80 | KMT2A (0.53) | GABRA1GABRB1GABRA3GABRB2KDM4E | |
| SCHEMBL29746408 | 0.72 | GABRP (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL553835 | 0.72 | GABRP (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10401861 | 0.72 | KDM4E (0.40) | KDM4EKDM3BKMT2ACSNK2A1PIM3 | |
| SCHEMBL4359910 | 0.72 | KDM4E (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10401860 | 0.72 | KDM3B (0.44) | KDM4EKDM3BKMT2ACSNK2A1PIM3 | |
| SCHEMBL30864233 | 0.71 | KDM4E (0.37) | KDM4EKDM3BKMT2ACSNK2A1PIM3 | |
| SCHEMBL7276703 | 0.68 | HTT (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8072226 | 0.68 | GABRP (0.68) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL16615908 | 0.68 | HCAR2 (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107250110-A | The noval chemical compound of (RET) inhibitor is reset as transfection | 葛兰素史克知识产权发展有限公司 | 2017-10-13 | — | — | CN | disclosed |