SCHEMBL4359910

SCHEMBL4359910

Nc1nc(=O)[nH]cc1C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.40
KDM3B Q7LBC6 1/20 0.40
TSHR P16473 1/20 0.39
NAPRT Q6XQN6 2/20 0.37
CSNK2A1 P68400 3/20 0.37
CSNK2A2 P19784 2/20 0.37
CSNK2B P67870 2/20 0.37
GABRP O00591 2/20 0.36
GABRD O14764 2/20 0.36
GABRA1 P14867 2/20 0.36
GABRB1 P18505 2/20 0.36
GABRG2 P18507 2/20 0.36
GABRB3 P28472 2/20 0.36
GABRA5 P31644 2/20 0.36
GABRA3 P34903 2/20 0.36
GABRA2 P47869 2/20 0.36
GABRB2 P47870 2/20 0.36
GABRA4 P48169 2/20 0.36
GABRE P78334 2/20 0.36
GABRA6 Q16445 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21223630 0.87 KDM3B (0.33) KDM4EKDM3BTSHRNAPRTCSNK2A1
SCHEMBL7209768 0.84 IKBKB (0.41) KDM4ETSHRPIM3CLK4ALDH1A1
SCHEMBL9149637 0.83 GABRP (0.33) KDM4EKDM3BNAPRTGABRPGABRD
SCHEMBL28361145 0.82 PBRM1 (0.38) KDM4ETSHRALDH1A1KMT2AADORA2A
SCHEMBL10580660 0.79 MAPT (0.47) ALDH1A1KMT2AADORA1MEN1MAPT
SCHEMBL532660 0.77
SCHEMBL932304 0.77
SCHEMBL3817207 0.77
SCHEMBL10401860 0.76 KDM3B (0.44) KDM4EKDM3BTSHRNAPRTCSNK2A1
SCHEMBL10401861 0.76 KDM4E (0.40) KDM4EKDM3BTSHRNAPRTCSNK2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2304 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747386-A1 DOUBLE-STRANDED OLIGONUCLEOTIDE AGENTS AND USES THEREOF Bisirna Therapeutics Pte. Ltd. (SG) 2026-05-27 EP claimed
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 CN claimed
US-20260125686-A1 COMPOSITIONS AND METHODS FOR MODULATION OF CFTR CYSTIC FIBROSIS FOUND (US) 2026-05-07 US claimed
WO-2026090560-A1 ENGINEERED NUCLEIC ACIDS AND USES THEREOF CRANK BIO, INC. (US) 2026-04-30 WO claimed
US-12606866-B2 Methods for the amplification of bisulfite-treated DNA THE UNIVERSITY OF CHICAGO (US) 2026-04-21 US claimed
US-12601006-B2 Targeted, long-read nucleic acid sequencing for the determination of cytosine modifications LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (CH) 2026-04-14 US claimed
EP-4713485-A2 SEQUENCING ADAPTERS FOR METHYLATION SEQUENCING Foundation Medicine, Inc. (US) 2026-03-25 EP claimed
US-20140322707-A1 COMPOSITION AND METHODS RELATED TO MODIFICATION OF 5-METHYLCYTOSINE (5-mC) THE UNIVERSITY OF CHICAGO (US) 2014-10-30 US claimed
EP-2791361-A1 METHODS AND KITS FOR DETECTION OF METHYLATION STATUS Oslo Universitetssykehus HF (NO) 2014-10-22 EP claimed
EP-2768975-A1 EPIGENETIC MARKER FOR THE IDENTIFICATION OF IL17 POSITIVE T CELLS IN COMPLEX SAMPLES Epiontis GmbH (DE) 2014-08-27 EP claimed
US-20140227703-A1 EPIGENETIC MARKER FOR THE IDENTIFICATION OF IL17 POSITIVE T CELLS IN COMPLEX SAMPLES EPIONTIS GMBH (DE) 2014-08-14 US claimed
WO-2014074453-A1 COMPOSITIONS AND METHODS FOR OXYGENATION OF NUCLEIC ACIDS CONTAINING 5-METHYLPYRIMIDINE NEW ENGLAND BIOLABS, INC. (US) 2014-05-15 WO claimed
WO-2014074450-A1 MAPPING CYTOSINE MODIFICATIONS NEW ENGLAND BIOLABS, INC. (US) 2014-05-15 WO claimed
US-20130244237-A1 Methods and Compositions for Discrimination Between Cytosine and Modifications Thereof and for Methylome Analysis NEW ENGLAND BIOLABS, INC. (US) 2013-09-19 US claimed
WO-2013138644-A2 METHODS AND COMPOSITIONS FOR DISCRIMINATION BETWEEN CYTOSINE AND MODIFICATIONS THEREOF, AND FOR METHYLOME ANALYSIS NEW ENGLAND BIOLABS, INC. (US) 2013-09-19 WO claimed
WO-2013090588-A1 METHODS AND KITS FOR DETECTION OF METHYLATION STATUS OSLO UNIVERSITETSSYKEHUS HF (NO) 2013-06-20 WO claimed
WO-2013057202-A1 EPIGENETIC MARKER FOR THE IDENTIFICATION OF IL17 POSITIVE T CELLS IN COMPLEX SAMPLES EPIONTIS GMBH (DE) 2013-04-25 WO claimed