Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28176151

N.O=C(OCCCO)OCCCO

nearest known ligand 0.36

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ACHE P22303 7/20 0.36
ALDH1A1 P00352 3/20 0.36
CAMK2A Q9UQM7 1/20 0.35
TSHR P16473 2/20 0.33
CYP3A4 P08684 1/20 0.33
ATM Q13315 1/20 0.32
GPR84 Q9NQS5 1/20 0.32
FFAR1 O14842 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
NAAA Q02083 1/20 0.31
CYP4F2 P78329 3/20 0.31
CYP4A11 Q02928 3/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL575125 0.97 ALDH1A1 (0.38) ACHEALDH1A1CAMK2ATSHRCYP3A4
SCHEMBL9287443 0.94 ACHE (0.36) ACHEALDH1A1CAMK2ATSHRCYP3A4
SCHEMBL2188513 0.92 TSHR (0.42) ACHEALDH1A1CAMK2ATSHRCYP3A4
SCHEMBL17368712 0.92 ACHE (0.44) ACHEALDH1A1TSHRCYP3A4GPR84
SCHEMBL575105 0.88 ACHE (0.45) ACHEALDH1A1CAMK2ATSHRCYP3A4
SCHEMBL575112 0.86 ACHE (0.48) ACHEALDH1A1TSHRCYP3A4GPR84
SCHEMBL9287648 0.86 ACHE (0.35) ACHEALDH1A1CAMK2ATSHRCYP3A4
SCHEMBL21143358 0.86 ACHE (0.48) ACHEALDH1A1TSHRCYP3A4GPR84
SCHEMBL21143379 0.86 ACHE (0.48) ACHEALDH1A1TSHRCYP3A4GPR84
SCHEMBL20437593 0.86 ACHE (0.44) ACHEALDH1A1CAMK2ATSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107266698-B Hydroxypropylation ammonium carbonate salts compound mixture, preparation method and purposes 唐宇煊 2018-02-13 CN disclosed
CN-107266698-A Hydroxypropylation ammonium carbonate salts compound mixture, preparation method and purposes 补天新材料技术有限公司 2017-10-20 CN disclosed