Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL27674344 | 1.00 | ALDH1A1 (0.57) | ALDH1A1CYP3A4POLBNPC1RAB9A | |
| Quinoline SCHEMBL27784188 | 0.95 | ALDH1A1 (0.52) | ALDH1A1CYP3A4POLBNPC1RAB9A | |
| Quinoline SCHEMBL15825305 | 0.90 | ALDH1A1 (0.53) | ALDH1A1CYP3A4POLBNPC1RAB9A | |
| Quinoxaline SCHEMBL28175254 | 0.86 | DRD2 (0.40) | ALDH1A1NPC1BCHEACHETP53 | |
| Quinoline SCHEMBL27902776 | 0.84 | ALDH1A1 (0.41) | ALDH1A1CYP3A4BCHEACHE | |
| Quinoline SCHEMBL27879944 | 0.84 | ALDH1A1 (0.41) | ALDH1A1CYP3A4BCHEACHE | |
| Quinoline SCHEMBL28280803 | 0.84 | ALDH1A1 (0.41) | ALDH1A1CYP3A4BCHEACHE | |
| Phenazine SCHEMBL28431056 | 0.84 | MAPT (0.44) | ALDH1A1POLBNPC1BCHEACHE | |
| Quinoline SCHEMBL28819404 | 0.84 | ALDH1A1 (0.68) | ALDH1A1CYP3A4POLBNPC1RAB9A | |
| Quinoline SCHEMBL27585762 | 0.82 | ALDH1A1 (0.51) | ALDH1A1POLBNPC1RAB9ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107438514-B | Optical article with photoluminescent indicia | 光学转变公司 | 2019-10-18 | — | — | CN | claimed |
| CN-105612228-B | Photochromic optical articles having allophanate protective coatings and methods of making the same | 光学转变公司 | 2018-03-30 | — | — | CN | claimed |
| CN-107438514-A | Optical article with photoluminescent indicia | 光学转变公司 | 2017-12-05 | — | — | CN | claimed |