Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2817679 | 1.00 | PGK1 (0.35) | PGK1PGK2CA2CA1TP53 | |
| SCHEMBL2985648 | 1.00 | PGK1 (0.35) | PGK1PGK2CA2CA1TP53 | |
| SCHEMBL2991217 | 0.86 | SMN1; SMN2 (0.36) | CA2CA1MMEECE1LAP3 | |
| SCHEMBL14502982 | 0.86 | SMN1; SMN2 (0.36) | CA2CA1MMEECE1LAP3 | |
| SCHEMBL11799913 | 0.86 | MME (0.33) | PGK1PGK2CA2MMEECE1 | |
| SCHEMBL2991220 | 0.86 | SMN1; SMN2 (0.36) | CA2CA1MMEECE1LAP3 | |
| SCHEMBL3102891 | 0.82 | ANPEP (0.32) | LAP3ALDH1A1 | |
| SCHEMBL2991880 | 0.82 | ALDH1A1 (0.50) | CA2CA1MMEALDH1A1 | |
| SCHEMBL2991878 | 0.82 | ALDH1A1 (0.50) | CA2CA1MMEALDH1A1 | |
| SCHEMBL3102882 | 0.82 | ANPEP (0.32) | LAP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101501050-B | Alpha-amino acid phosphonic acid compounds, method of preparation and use thereof | THERMPHOS TRADING GMBH | 2013-10-30 | — | — | CN | disclosed |
| US-8505626-B2 | α-Amino acid phosphonic acid compounds, method of preparation of use thereof | DEQUEST AG (CH) | 2013-08-13 | — | — | US | disclosed |
| EP-2054423-B1 | ALPHA-AMINO ACID PHOSPHONIC ACID COMPOUNDS, METHOD OF PREPARATION AND USE THEREOF | DEQUEST AG (CH) | 2012-07-18 | — | — | EP | disclosed |
| US-20100186961-A1 | ALPHA AMINO ACID PHOSPHONIC ACID COMPOUNDS, METHOD OF PREPARATION OF USE THEREOF | THERMPHOS TRADING GMBH | 2010-07-29 | — | — | US | disclosed |
| EP-2054423-A1 | ALPHA-AMINO ACID PHOSPHONIC ACID COMPOUNDS, METHOD OF PREPARATION AND USE THEREOF | Thermphos Trading GmbH (CH) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008017339-A1 | α-AMINO ACID PHOSPHONIC ACID COMPOUNDS, METHOD OF PREPARATION AND USE THEREOF | THERMPHOS TRADING GMBH (CH) | 2008-02-14 | — | — | WO | disclosed |
| EP-1887011-A1 | Alpha amino acid phosphonic acid compounds, method of preparation and use thereof | Thermphos Trading GmbH (CH) | 2008-02-13 | — | — | EP | disclosed |