Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6848244 | 0.84 | PPID (0.51) | PPIDSMN1; SMN2STING1PTPN1ALDH1A1 | |
| SCHEMBL3614552 | 0.83 | ALDH1A1 (0.52) | SMN1; SMN2PTPN1ALDH1A1MAPTCYP2C9 | |
| SCHEMBL21611670 | 0.83 | STING1 (0.54) | PPIDSMN1; SMN2STING1ALDH1A1EPHX1 | |
| Hydrochloric Acid SCHEMBL8836394 | 0.82 | PPID (0.50) | PPIDSMN1; SMN2STING1PTPN1ALDH1A1 | |
| SCHEMBL11500809 | 0.81 | ALDH1A1 (0.53) | PPIDSMN1; SMN2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL17962571 | 0.81 | EPHX2 (0.51) | PPIDSMN1; SMN2STING1L3MBTL1EPHX2 | |
| SCHEMBL27625428 | 0.80 | EPHX2 (0.50) | SMN1; SMN2ALDH1A1L3MBTL1CYP2C9EPHX1 | |
| SCHEMBL28239404 | 0.80 | GAA (0.55) | PPIDSMN1; SMN2STING1EPHX1EPHX2 | |
| Ammonia Solution, Strong SCHEMBL27925842 | 0.80 | ALDH1A1 (0.52) | PPIDSMN1; SMN2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL15656106 | 0.80 | MEN1 (0.53) | PPIDSMN1; SMN2STING1MAPTEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104672250-B | Substituted heteroaryl compound and combinations thereof and purposes | 广东东阳光药业有限公司 | 2017-11-07 | — | — | CN | disclosed |